Kenneth Frazier

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After graduating from Harvard, Frazier began his law career with Drinker Biddle & Reath in Philadelphia. In 1991, Esther F. Lardent, head of the Death Penalty Representation Project, asked Frazier to defend death-row inmate James Willie "Bo" Cochran. Cochran had been arrested and accused of murdering an assistant manager at a Birmingham grocery store in 1976. Frazier, then a partner at Drinker Biddle, and two colleagues took the case. In 1995, after 19 years on death row, the United States Courts of Appeals for the Eleventh Circuit overturned Cochran's conviction. In 1997, Cochran was retried and found not guilty. Frazier continued to represent him after leaving Drinker Biddle. During Frazier's law career, he also took four summer sabbaticals to teach trial advocacy in South Africa.

As a lawyer at Drinker Biddle, one of Frazier's clients was Merck & Co., the second-largest drug company in the United States. In 1992, he joined Merck's public affairs division as general counsel. Frazier was named senior general counsel in 1999. As general counsel, he was credited with overseeing the company's defense against claims that the anti-inflammatory drug Vioxx had caused heart attacks and strokes. Analysts at the time estimated Merck's liability to range from 20 to 50 billion dollars. Frazier said the case was "the most significant challenge [he'd] ever faced." He chose to fight all cases in court rather than settle them all quickly. The remaining cases were settled in 2007 for $4.85 billion.

In 2006, Frazier was promoted to executive vice president in addition to his role as general counsel. He led the company's largest group, Human Health, from 2007 until he was named president of Merck in April 2010. On January 1, 2011, he became CEO and a member of the company's board of directors, replacing former Merck CEO Richard Clark. Frazier is the first African-American to lead a major pharmaceutical company.

As CEO, Frazier has directed the company to take financial risks in developing new treatments. In 2013, he prioritized research funding over meeting the year's earnings target. He has placed special emphasis on improving treatments for Alzheimer's disease. Frazier's father died from Alzheimer's. Frazier has said he is also motivated at Merck by a desire to improve the lives of people in developing countries.

Frazier received a total compensation of $21,387,205 in 2014; $17,023,820 in 2015; and $21,781,200 in 2016. On February 26, 2017, it was reported Frazier owned 600,304 shares of Merck stock worth approximately $37,000,000. Based on stock transactions at Merck alone and his tenure at the company, his net worth is in the hundreds of millions. As of December 31, 2016, Mr. Frazier was eligible for early retirement subsidies under the Qualified Plan and SRP with a pension valued at $26,593,261. In the "annual collaborative report" from Equilar and The New York Times, Frazier ranked 66th in the May 2015 list of "200 highest-paid CEOs of large publicly traded companies" and seventh in the list of biopharmaceutical executives with the highest total compensation.

In July 2016, Frazier sold 60,000 shares of the firm's stock. The stock was sold at an average price of $64.44. In the years 2018, 2019 and 2020 respectively Frazier sold 787,792, 694,698 and 280,000 shares of the firm's stock with a total value at time of sale of $110.23 million. On February 4, 2021, Merck announced that Frazier would be retiring as president and CEO at the end of June, while remaining executive chairman.

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