Premiered Date
September 12, 1966
Network
CBS
1958-1976

Anissa Jones

as Ava Elizabeth 'Buffy' Patterso

1921-1997

Brian Keith

as Uncle Bill Davis

1918-1977

Sebastian Cabot

as Mr. Giles French

76

Kathy Garver

as Catherine 'Cissy' Patterson-Da

About Family Affair

About

A well off engineer tries to raise his brother's orphaned children in a New York City apartment. 

Trivia

The show was created by the minds behind My Three Sons and The Millionaire. They were nominated for eight Emmys including Outstanding Comedy Series in 1969.