At 41 years old, Natalie Dormer has this physical status:
Six months after graduating from Webber Douglas, Dormer won the role of Victoria in Casanova. Her film debut, it was released in 2005. The director, Lasse Hallström, was so impressed with Dormer's comedic timing, he ordered the scriptwriter to expand her part. In 2005, Dormer had a small part in Distant Shores. After the filming of Casanova, Dormer was out of work for ten months, which she ascribes to "bad representation". She was attached to an independent film although financing caused delays. Removed from the audition circuit, Dormer worked as a waitress and data entry. She says her out-of-work phase "was the best lesson".
In 2007 and 2008, Dormer played Anne Boleyn in the first two seasons of The Tudors, for which she received highly positive reviews. Robert Abele of LA Weekly wrote: "Natalie Dormer presents a painterly exquisiteness and complexity in her portrayal of Anne Boleyn... her enigmatic, time-halting loveliness is a boon for The Tudors, and damn near worth losing your head over". After her character's death at the end of the second season, The Boston Herald noted: "Dormer gave Anne Boleyn life, making her not just a beautiful schemer but a rebellious, defiantly independent tragic hero in the tradition of Rebel Without a Cause and Cool Hand Luke... her departure from The Tudors leaves a tremendous void."
In 2008, Dormer played Moira Nicholson in Agatha Christie's Marple: "Why Didn't They Ask Evans?" and appeared in the film City of Life. Dormer's Marple appearance aired in the US in the summer of 2009 as part of the PBS Masterpiece Mystery anthology series. Also in that year, she appeared in Incendiary, but her scenes were cut from the final film. Following Marple, Dormer went on to film some new roles, including the Duchess of York in Madonna's film W.E., Pvt. Lorraine in Captain America: The First Avenger, and Niamh Cranitch in the BBC court drama Silk. She returned to The Tudors as Anne Boleyn in a dream sequence for the fourth and final season in mid-2010.
In March 2010, Dormer debuted at the Young Vic theatre in London as Mizi in the play Sweet Nothings. In The Observer, theatre critic Susannah Clapp praised the performances of the cast and wrote: "Natalie Dormer is lissome as a dirty, delightful gadabout, pushing aside an entire chess game to put down her hat". She received a commendation for her performance at the Ian Charleson Awards 2010. Her next stage role was Pat in .45 at Hampstead Theatre in November 2010.
From 2012 to 2016, Dormer played Margaery Tyrell in the HBO fantasy TV series Game of Thrones. She received international recognition for the role, and she received critical acclaim for her performance. Dormer, along with the rest of the ensemble cast, was nominated for four Screen Actors Guild Award for Outstanding Performance by an Ensemble in a Drama Series in 2012, 2014, 2015, and 2016, and the cast was awarded the Empire Hero Award in 2015 by the Brit film magazine Empire. For her performance in the third season of the show, Dormer won the Ewwy Award for Best Supporting Actress – Drama.
In March 2012, Dormer worked at the Young Vic to play the title role in After Miss Julie by Patrick Marber. Her performance earned acclaim, with reviews describing her as "little short of sensational", "outstanding", and "the perfect Miss Julie". The online theatre magazine Exeunt says her portrayal of Miss Julie contained "all the anger, desire, wit, loneliness, merriment, melancholy and desperation of the casts of several plays together... Dormer has more presence and eerie beauty than is apparent from her appearances on-screen, and she shape-shifts almost supernaturally between seductress, child, and tormentor."
In March 2013, she played the Lady Door in the radio play of Neverwhere, based on the novel by Neil Gaiman. Later that year, she appeared in the car racing drama Rush and the thriller The Counselor. She appeared in A Long Way From Home. In 2013, Dormer played Irene Adler in the final three episodes of the first season of the CBS series Elementary; she reprised the role in the second season. A November 2014 press-release said Dormer was to star as the scandalous 18th-century noblewoman Lady Worsley in a BBC drama called The Scandalous Lady W, based on the book Lady Worsley's Whim by the historian Hallie Rubenhold; it aired in August 2015. Dormer also played Cressida in the final two films in The Hunger Games franchise, which were released in 2014 and 2015. For the role, she shaved the left side of her head. Both films were financial successes, with the former grossing $755.4 million and the latter grossing $658.3 million, ranking as Dormer's highest grossing releases to date.
In August 2016, Dormer worked in The Professor and the Madman alongside Mel Gibson and Sean Penn. Dormer starred in the Lava Bear Films/David S. Goyer-produced horror film The Forest, directed by music video and short-film director Jason Zada as his feature film debut. Focus Features has the North American distribution rights to the film released in January 2016.
In September 2014, Deadline Hollywood announced Dormer was cast in Screen Gems' action thriller Patient Zero, alongside Matt Smith and Game of Thrones co-star John Bradley. The film was directed by Oscar-winning filmmaker Stefan Ruzowitzky based on a script by Mike Le. Patient Zero was released through video on demand on 14 August 2018, before receiving a limited theatrical release on 14 September 2018, by Vertical Entertainment. A February 2017 press-release announced Dormer was cast as schoolteacher Mrs Hester Appleyard in Picnic at Hanging Rock, an adaptation of the 1967 Australian novel of the same name by Joan Lindsay. The six episode feature aired on Amazon Prime and on BBC2 in the United Kingdom. Dormer's performance was described as "commanding" and "delicious".
Dormer returned to the stage at the Theatre Royal Haymarket in October 2017 for the lead role in David Ives' Venus in Fur. The Telegraph described her performance as "sensational" while Lyn Gardner says Dormer was "dominant in every way". She co-wrote the film In Darkness, released in July 2018, with her ex-fiancé Anthony Byrne. Each describe writing together as "challenging". The film was criticised for scenes of "gratuitous nudity". During an interview with The Guardian, she says "There has to be sex in the power play of a thriller. We all got bodies, after all. In this film, the love-making scene is a metaphor for the way my character connects with the part played by Ed Skrein. Nakedness is a good equaliser, and the shower scene also shows the tattoos on my character’s body and makes it clear she is not quite who you think."
Following her audio work on Neverwhere, a August 2018 press-release announced Dormer would narrate the audiobook for Pottermore Publishing’s Harry Potter: A History of Magic. Of the role, Dormer says she "always adored the Harry Potter books" and it was "fun to join the wizarding world family". In October 2018, it was announced that she would play Vivien Leigh in miniseries Vivling. The series focuses on Leigh's classic films, including Gone with the Wind and A Streetcar Named Desire. Dormer will develop and produce the show. In 2019, she was the voice of Onica in The Dark Crystal: Age of Resistance.
In December 2019, Dormer's production company, Dog Rose Productions, signed a multi-year first-look deal with Fremantle. The Vivling miniseries will be Dormer's first production through the deal. In 2020, she starred in Showtime's series, Penny Dreadful: City of Angels, playing multiple roles; she received praise for her work on the series, and she was nominated for an award at the Critics' Choice Super Awards.