At 27 years old, Lele Pons has this physical status:
Pons began her career on the video platform Vine. She has said she used Vine to showcase the creative things she was already doing. Speaking to Teen Vogue, Pons said, "I started with my friends, and I started becoming bad. At first it was just being really creative - it wasn't even funny stuff." Her follower base continued to grow and Pons has said that it "got to the point where a lot of people depended on me to make them... just so they could get a laugh." She became the first "Viner" to reach one billion loops.
Writing in The Cut, Allie Jones described Pons' comedy as "universal, physical, and complete with a twist ending". Pons' comedic style has also been criticised. For instance, former Viner, Cody Ko, critically viewed one her sketches, saying, "This was written by a four-year-old." Pons cites, among her inspirations, several Latin American female stars such as Sofía Vergara, Gaby Espino, and Shakira. In 2016, she was signed with entertainment company Shots Studios.
Pons is managed by John Shahidi of Shots Studios.
Pons has used her success in Internet comedy to launch a number of enterprises. In 2015, she launched a jewelry collection called UNO Magnetic. In 2016, Pons co-authored a novel based on her own high school experiences, Surviving High School, co-authored with Melissa de la Cruz. Pons starred as Callie in the 2016 romantic comedy We Love You, released on YouTube Red. In the movie, characters played by Yousef Erakat and Justin Dobies both fall for Pons, who is "cool enough" to date both of them at the same time. The movie was produced by YouTube and AwesomenessTV.
Pons appeared in the first episode of MTV's horror TV series, Scream, in which she was the season's first victim. She has starred in a number of music videos, including "Havana" by Camila Cabello, and "Downtown" by Anitta and J Balvin. In May 2018, Pons released her debut single, a Spanish-language duet with Matt Hunter titled "Dicen". The YouTube music video amassed 10 million views in just four days. Pons has also had success in modelling. In February 2017, she became a brand ambassador for CoverGirl. The same month, Pons walked in a Dolce & Gabbana show in Milan. Babe criticised the move as seeming "a bit hackneyed and past-it". In August, Pons released her first single and music video for her song "Celoso", which was directed by fellow creator Rudy Mancuso. The song was certified 10× Diamond and earned a nomination for the Premios Lo Nuestro nomination for the video. On March 29, 2019, Lele released her English-language debut, and her first country song with the Jake Owen duet "Señorita" from his album Greetings from... Jake.
Pons took over hosting of La Voz... México on October 14, 2018. She presented the 19th Annual Latin Grammy Awards with Aitana.
On December 6, 2019, Pons released her new single and music video "Vete Pa La". The music video was self-directed and edited by Pons and produced by Shots Studios.
In December 2019, Pons was a co-host on the red carpet alongside Chelsea Briggs for the 2019 Billboard Women in Music.
Pons was a guest speaker at the 2020 CES conference held in Las Vegas. As a digital media mogul and global entertainer, Pons was asked to be a speaker on the Spotify panel alongside Spotify's Chief Content Officer Dawn Ostroff. She talked about how Spotify revolutionized music and impacted her career and how she plans on using that same model for her upcoming podcast with Spotify.
On August 19, 2020, Pons released the first episode of Best Kept Secrets with Lele Pons, a podcast on Spotify in which anonymous callers share "eyebrow raising experiences they don't dare share with friends and family".