Osmosis Jones

Released Date
August 10, 2001
Distributor
Warner Bros.
Genre
Comedy
Rating
PG
Worldwide Gross
Domestic Gross + International Gross = Worldwide Gross
$13,596,911 + $429,507 = $14,026,418
59
Chris Rock

as Osmosis

45
Brandy

as Leah Estrogen

74
Bill Murray

as Frank Detorre

53
Kid Rock

as Kidney Rock (voice)

93
William Shatner

as Mayor Phlegmming

72
Rodger Bumpass

as Announcer

70
Ron Howard

as Tom Colonic

63
Laurence Fishburne

as Thrax

60
Molly Shannon

as Mrs. Boyd

62
Carlos Alazraqui

as Spanish Germ

64
Chris Elliott

as Bob Detorre

65
David Hyde Pierce

as Drixenol

72
Joel Silver

as Police Chief

87
David Ossman

as Scabies

About Osmosis Jones

A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.

About

Set inside a human being named Frank, a policeman white blood cell and a cold pill must stop a deadly virus from taking down their inhabitant. 

Trivia

The Farrelly brothers, Peter and Bobby, were hired to direct the live action sequences for the film. Tom Sito and Piet Kroon directed the animated parts.