At 27 years old, Swae Lee has this physical status:
In 2013, he and Slim Jxmmi signed to Mike Will Made It's label EarDrummers Entertainment as Rae Sremmurd. They have since released three studio albums under EarDrummers, SremmLife, SremmLife 2, and SR3MM.
In March 2015, Swae Lee was featured on Mike Will Made It's "Drinks on Us", which also featured artists Future and The Weeknd, and became his first single as solo artist. In September 2015, he was featured on Wiz Khalifa's "Burn Slow", which peaked at number 83 on the Billboard Hot 100, making it Swae Lee's first solo entry on the chart.
In April 2017, Swae Lee was featured on French Montana's "Unforgettable". The song peaked at number three on the Billboard Hot 100, making it Swae Lee's first top ten single on the chart as a solo artist. In September 2018, Jhené Aiko featured Swae Lee on her track "Sativa". Two months later, Swae Lee released a song titled "TR666" alongside Trippie Redd. On May 4, 2018, almost two years after its initial announcement in August 2016, Swae Lee released his debut solo album, Swaecation as a part of a triple album set, which also contained Rae Sremmurd's third studio album, SR3MM and Slim Jxmmi's debut studio album as a solo artist, Jxmtro. In October 2018, he featured on the song "Close to Me" by Ellie Goulding and Diplo. Swae Lee also collaborated on XXXTentacion's song "Arms Around You" after his death, along with Lil Pump and Maluma. On October 18, 2018, Swae Lee featured on Post Malone's song "Sunflower" for Spider-Man: Into the Spider-Verse, which became Post Malone's third and Swae Lee's first song as a soloist to top the Billboard Hot 100. He appeared on Nicki Minaj’s 2018 album Queen.
In May 2019, he collaborated on the song "Crave" with Madonna on her album Madame X. In August 2019, Swae Lee released "Won't Be Late" featuring Canadian rapper and singer Drake, produced by Tekno and Mike Will Made It. In October 2019, he was featured on 88rising's "Walking", alongside Joji, Jackson Wang, and Major Lazer. As of 2020, he released the single "Someone Said", a reworked version of Travis Scott's "Sicko Mode". He also collaborated with Chloe x Halle on the Mike Will Made It-produced "Catch Up", from the former's album Ungodly Hour. He was featured on the remix to Arizona Zervas' hit song "Roxanne". On June 18, 2020, Swae Lee released the single, "Reality Check".
Swae Lee invested in esports organization XSET in October 2020. Swae Lee has been working on his upcoming album Human Nature since 2020. In the same year, he appeared on Pop Smoke’s posthumous album Shoot for the Stars, Aim for the Moon. In 2021, he collaborated with Alicia Keys on the single "Lala (Unlocked)" at the 2021 MTV Video Music Awards.
Calvin Harris has shared a glimpse of his upcoming single, "New to You," on social media, also announcing that it will be a collaboration with Offset, Normani, and Tinashe. The song, which will be released on 29 July, is the fourth single from Harris's forthcoming album, "Funk Wav Bounces Vol. 2."