Michael Elias DeBakey

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DeBakey joined the faculty of Baylor University College of Medicine (now known as the Baylor College of Medicine) in 1948, serving as chairman of the surgical department until 1993. DeBakey was president of the college from 1969 to 1979, and served as its chancellor from 1979 to January 1996, when he was named chancellor emeritus. He was Olga Keith Wiess and Distinguished Service Professor in the Michael E. DeBakey Department of Surgery at Baylor College of Medicine and director of the DeBakey Heart Center for research and public education at Baylor College of Medicine and Houston Methodist Hospital.

DeBakey was a member of the medical advisory committee of the Hoover Commission and was chairman of the President's Commission on Heart Disease, Cancer and Stroke during the Johnson Administration. He worked in numerous capacities to improve national and international standards of health care. Among his numerous consultative appointments, he served 3 terms on the National Heart, Lung, and Blood Advisory Council of the National Institutes of Health.

DeBakey hired surgeon Denton Cooley at Baylor College of Medicine in 1951. They collaborated until Cooley's resignation from his faculty position at the college in 1969.

In 1980 DeBakey was a consultant in the care of Mohammad Reza Pahlavi, the exiled Shah of Iran, who was in the terminal stages of lymphoma. Due to hypersplenism, the Shah underwent splenectomy in Cairo on March 28, 1980, with DeBakey supervising a team of surgeons. At operation, the Shah was found to be harboring widely metastatic disease. Several complications developed in the postoperative period, including a subphrenic abscess and pneumonia. Although these were successfully treated, the Shah succumbed from his malignancy on July 27.

In the 1950s, DeBakey's observations and classification of atherosclerotic blood vessels permitted innovations in the treatments of vascular disease. His pursuit of the ideal material to make grafts led him to a department store that had run out of nylon, so he settled on polyethylene terephthalate (Dacron) and bought a yard of the material. Using his wife's sewing machine, DeBakey produced the first arterial Dacron grafts to replace or repair blood vessels. He subsequently collaborated with a research associate from the Philadelphia College of Textiles and Science to create a knitting machine for making grafts.

DeBakey performed the first successful carotid endarterectomy in 1953. A year later, he pioneered techniques in grafts for the various parts of the aorta.

DeBakey was among the earliest surgeons to perform coronary artery bypass surgery. A pioneer in the development of an artificial heart, he was among the first to use an external heart pump successfully in a patient – a left ventricular bypass pump.

In 1958, to counteract narrowing of an artery caused by an endarterectomy, DeBakey performed the first successful patch-graft angioplasty. This procedure involved patching the slit in the artery from an endarterectomy with a Dacron or vein graft. The patch widened the artery so that when it closed, the channel of the artery returned to normal size.

In the 1960s, DeBakey and his team of surgeons performed some of the early instances of surgeries on film.

DeBakey founded and chaired the Foundation for Biomedical Research (FBR), whose goal is to promote public understanding and support for animal research. DeBakey made wide use of animals in his research. He antagonized animal rights and animal welfare advocates who oppose the use of animals in the development of medical treatment for humans when he claimed that the "future of biomedical research; and ultimately human health" would be compromised if shelters stopped turning over surplus animals for medical research. Responding to the need for animal research, DeBakey stated that "These scientists, veterinarians, physicians, surgeons and others who do research in animal labs are as much concerned about the care of the animals as anyone can be. Their respect for the dignity of life and compassion for the sick and disabled, in fact, is what motivated them to search for ways of relieving the pain and suffering caused by diseases."

Later surgical career

DeBakey continued to practice medicine until his death in 2008 at the age of 99. His contributions to the field of medicine spanned the better part of 75 years. DeBakey operated on more than 60,000 patients, including several heads of state. DeBakey and a team of American cardiothoracic surgeons, including George Noon, supervised quintuple-bypass surgery performed by Russian surgeons on Russian president Boris Yeltsin in 1996.

In late 2005, DeBakey suffered an aortic dissection. Years prior, DeBakey had pioneered the surgical treatment that now bears his name to treat this condition. A sharp chest pain sent him to Houston Methodist Hospital, where the diagnosis was confirmed by a CT scan. DeBakey initially resisted the surgical option, but as his health deteriorated and DeBakey became unresponsive, the surgical team opted to proceed with surgical intervention. In a controversial decision, Houston Methodist's ethics committee approved the operation; on February 9–10, DeBakey at age 98 became the oldest patient ever to undergo the surgery for which he was responsible. The operation by George Noon to repair his aorta with a Dacron graft, similar to one he had pioneered decades earlier, lasted seven hours. After a complicated post-operative course that required eight months in the hospital at a cost of over one million dollars, DeBakey was released in September 2006 and returned to good health to live for another two years.

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